CHEMICAL COMPOSITION AND ANTIMICROBIAL ACTIVITY OF HARAMAYA PROPOLIS (BEE GLUE), ETHIOPIA
AbstractThe present study was aimed at investigating the chemical composition and antifungal activity of Ethanol Extracted Haramaya propolis (EEHP). The GC-MS analysis of EEHP showed the presence of sixteen compounds and twelve compounds were identified by means of their retention times, by comparison of their mass spectra with the NIST 2005 library data and literature. The major constituents of EEHP were Benzenamine, N, N-dibutyl- (21.94%), Paromomycin (9.74%), 4-Aminobutyramide, N-methyl-N-[4-(1-pyrrolidinyl)-2-butynyl]- (9.26%) and DL-Tryptophan, 5-methoxy (7.43%). The Crude EEHP showed antifungal activities against Fusarium sp., Aspergillus niger and Colletotrichum sp. GC-MS results showed that the antifungal activities of Haramaya propolis could be because of the presence of 3-(α-Hydroxyethyl)-aniline, Benzenamine,N, N-dibutyl, DL-Tryptophan,5-methoxy, 6-Amino-5, 8-dimethoxyquinazoline, Paromomycin and Imidazole, 2-fluoro-5-[2-carboxyvinyl].
Article Information
29
734-740
654KB
1286
English
IJPSR
Kesatebrhan Haile*and Aman Dekebo
Department of Chemistry, Haramaya University, P.O. Box: 138, Haramaya, Ethiopia
kesete06@gmail.com
26 October, 2012
01 December, 2012
28 January, 2013
http://dx.doi.org/10.13040/IJPSR.0975-8232.4(2).734-40
01 February, 2013
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