CHEMICAL COMPOSITION, ANTIMICROBIAL AND ANTIOXIDANT PROPERTIES OF BARRINGTONIA ACUTANGULA BARK EXTRACT
AbstractBarringtonia acutangula (L.) Gaertn. (Family: Lecythidaceae), is a medium-sized tree found throughout India. It has been used in folk medicine to treat tuberculosis, skin disease, inflammation, hemorrhoids and diarrhea. The present study deals with in-vitro antioxidant, antimicrobial and GC-MS study on the bark extract of B. acutangula. In order to investigate the antioxidant activity, reducing power activity was used. Antibacterial activity was evaluated by disc diffusion method. Identification of extract bioactive compounds by GC-MS revealed that alpha-Pinene oxide, 1,2-benzoldicarbonsaeure di-(hex-1-en-5-yl-ester), 3-methyl-4-heptanone, (Z)-3-hexadecene are the major components. The antioxidant activity of the bark extract increased with increasing concentration; the values are comparable with the standard antioxidant ascorbic acid. From the results of antibacterial activity, B. acutangula bark extract could inhibit gram-negative and gram-positive pathogenic bacteria. Thus, B. acutangula could be considered as an excellent broad-spectrum antibacterial agent.
Article Information
37
1401-1406
1170 KB
339
English
IJPSR
Thrisha Venkatajalapathi
Department of Biochemistry, Ethiraj College for Women (Affiliated to University of Madras), Egmore, Chennai, Tamil Nadu, India.
thrishavenkat@yahoo.com
17 July 2022
29 August 2022
02 September 2022
10.13040/IJPSR.0975-8232.14(3).1401-06
01 March 2023
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