CHEMICAL CONSTITUENTS OF THE ANTIDIABETIC PLANT RAVENALA MADAGASCARIENSIS
AbstractRavenala madagascariensis Sonn. is one of the most popular medicinal plants in Madagascar, India and several African countries. It is used in the treatment of many diseases, and particularly in those of diabetes. The duration of treatment, often for life, and its relatively high cost for certain social categories, constrain more and more patients to use this plant. Its chemical constituents were still little studied and this problem could create significant damage in case of intoleranceor abuse during its use.The present study undertaken on the leaves of Ravenala madagascariensis, led to the isolation and structural elucidation of two new compounds (1 and 2), together with the known cycloartanol triterpene (3) which was isolated for the first time from this plant. Their structures were elucidated as (2E, 7R, 11R) phytyl-3, 7, 11, 15-tetramethylhexadec-2-enyl pentadecanoate (1) and (24S, 31S)-cycloartan-31, 32-diol (2). Structural determinations were made on the basis of analysis of 1D and 2D-NMR spectroscopic data. The complete 1H and 13C resonance assignments were also carried out by using 1H-1H COSY, HSQC, NOESY and HMBC experiments
Article Information
58
5503-5510
515KB
1392
English
IJPSR
H. Ramiarantsoa *, P. A. Yao-Kouassi, C. Kanko , K.M. Assi , A. L. Djakoure and F. Z. Tonzibo
Laboratoire de Chimie Organique Biologique UFR-SSMT Universite Université Félix Houphouët-Boigny, 22 BP 582, Abidjan, Côte d’Ivoire
rharisolo@yahoo.fr
13 May, 2014
29 July, 2014
19 November, 2014
http://dx.doi.org/10.13040/IJPSR.0975-8232.5(12).5503-10
01 December 2014
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