COLLECTION AND DATA-MINING OF BIOACTIVE COMPOUNDS WITH CANCER TREATMENT PROPERTIES IN THE PLANTS OF FABACEAE FAMILYAbstract
Medicinal plants therapeutic agents are a big source of information for a wide variety of chemical constituents which could be developed as new drugs. The present study focused on anticancer, antitumor anticarcinogenic and cancer preventive activities of bioactive compounds found in plants belonging to Fabaceae family. The bioactive compounds and their scientific details were mining from publically available phytochemical databases (Dr. Duke’s phytochemistry and ethnobotanical database and USDA phytochemical database). Fabaceae family is one of the largest family which includes 18,860 plant species, of them, 12 plant species were identified to posses 106 bioactive compounds related to cancer treatment. The plant species such as Acacia nilotica, Arachis hypogaea, Cajanus cajan, Crotalaria juncea, Glycine max, Mimosa pudica, Pisum sativum, Psoralea esculenta, Tamarindus indica, Trifolium pratense, Trigonella foenum-graecum and Vigna subterranean possess bioactive compounds leading to cancer treatment. The important and mostly studied phytochemical compounds are Beta carotene, Alpha tocopherol, Alanine, Genestein, Caffeic acid, Tannin, Alpha carotene, Ascorbic acid, Limonene, Daidzein, Rutin and Niacin.
Balan Velusamy, Saravanan Kaliyaperumal* and Arulpriya Raju
PG & Research Department of Zoology, Nehru Memorial College (Autonomous) Puthanampatti, Tiruchirapalli, Tamilnadu, India.
07 December, 2015
26 January, 2016
07 February, 2016
01 May 2016