COMPARATIVE STUDY OF HYPOGLYCEMIC EFFECT OF ETHANOLIC AND HOT WATER EXTRACTS OF ANDROGRAPHIS PANICULATA IN ALLOXAN INDUCED RATAbstract
The aim of present study was to investigate the potential roles of ethanolic and hot water extracts of Andrographis paniculata on reducing the blood sugar level (BSL) in alloxan- induced rats. Oral administration of ethanolic (2 g/kg b. w.) and hot water (0.8 g/kg b. w.) extracts of Andrographis paniculata showed the antidiabetic properties and decreased the blood glucose level by 33.71% (p<0.0001) and 39.69% (p<0.0001) respectively in alloxan induced (40mg/kg b.w.) rats. The results were also compared with that of diabetic control rats.
Anusua Chowdhury and Subrata Kumar Biswas
Assistant Professor, Department of Pharmacy, BGC Trust University, BGC Biddyanagar, Chandanaish, Chittagong, Bangladesh
27 October, 2011
03 February, 2012
23 February, 2012