COMPARING THE EFFICACY AND PHARMACOECONOMICS OF ATORVASTATIN AND ROSUVASTATINAbstract
The aim of the research work was to determine and compare the efficacy and pharmacoeconomics of Atorvastatin and Rosuvastatin. The cohort, observational, and prospective studies were conducted at KMC multispeciality hospital, Trichy. The hyperlipidemic patient was treated with Atorvastain (10 mg) and Rosuvastatin (5 mg) every day over a period of six months. Contemplating the inclusion and exclusion criteria, 104 patients were selected for the study. From the selected 104 patients, 52 patients were treated with Atorvastatin (Group- A) and Rosuvastatin (Group- B). The therapeutic effect of both drugs was compared. The level of Total cholesterol (TC), Triglyceride (TG), Low-density lipoprotein (LDL), and High-density lipoprotein (HDL) were estimated. Rosuvastatin-treated patient’s reports showed a significant reduction in total cholesterol, triglyceride, and low-density lipid-protein, and increased the high-density lipoprotein during the therapy compared to Atorvastatin treated patient’s group. The results revealed that Rosuvastatin is more effective than Atorvastatin and Rosuvastain is cost effective than Atorvastatin.
N. Vanisri *, K. Sakthivel and S. Akilandeswari
Department of Pharmacy Practice, Srinivasan College of Pharmaceutical Sciences, NH-45 Trichy Chennai Trunk Road, Samayapuram, Trichy, Tamil Nadu, India.
03 February 2022
08 March 2022
27 April 2022
01 September 2022