COMPUTATIONAL PREDICTION OF BLOOD-BRAIN PARTITIONING OF DRUGS
AbstractIncreasing use of bioinformatics made very easy to researchers in biological and drug discovery field. Bioinformatics is involved at each and every step of drug discovery to drug development. The first step of the drug discovery is a question about disease and the treatment by drugs and whenever term drug comes, means something has to be given and the second question arises the given compound is drugable or not. To check any drugable compound the compound has to be cleared by the ADME studies and the main sensitive parameter blood brain barrier. Bioinformatics made it easy without use of model organism and waste of time. In this study we aimed to predict the blood brain barrier parameters on 87 drugs about their drug ability.
Article Information
48
339-341
329
1112
English
IJPSR
P. Shankar *, P. Lakhani, D. K. Singh, S. Tutu, S.N. Sankhawar, A. K. Sachan and R. K. Dixit
Department of Pharmacology and Therapeutics, King George’s Medical University, Lucknow, Uttar Pradesh, India
pratap.mbi@gmail.com
19 July, 2016
21 September, 2016
26 September, 2016
10.13040/IJPSR.0975-8232.8(1).339-41
01 January, 2017
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