CYTOTOXIC ACTIVITY OF METHANOL AND DICHLOROMETHANE EXTRACTS SOFT HALICONA SPECIESAbstract
The study was aimed to evaluate the anticancer activity of the Soft Halicona species on the HeLa cell line. The Soft Halicona species methanol and Dichloromethane extracts were tested for its inhibitory effect on HeLa cell line. The percentage viability of the cell line was carried out by using colorimetric method. The cytotoxicity of Soft Halicona specieson HeLa cell was evaluated by MTT assay. Both the methanol and Dichloromethane extract has significant cytotoxic effect on HeLa cell line in concentration range between 0.1µg/ml to 100µg/ml by using MTT assay. R2 value of Soft Halicona species on HeLa cell of methanol extract was 0.8316 and for dichloromethane extract was 0.6699 and percentage cell inhibition for methanol extract 61.40% and Dichloromethane extract was 46.98%.
Narasimharaju Alluri*, L.H. Thameemulansari and C. UmaMaheswara Reddy
Sri Ramachandra college of Pharmacy, Sri Ramachandra University, Chennai, Tamil Nadu, India
20 February, 2012
02 April, 2012
23 May, 2012
01 June, 2012