DERMATOLOGICAL ADVERSE DRUG REACTIONS IN TERTIARY CARE HOSPITALAbstract
Adverse drug reactions are undesirable effects of drugs beyond its anticipated therapeutic uses occurring commonly in clinical practice. Although many of these ADRs are mild and disappear when the suspected drug is stopped or dose is reduced, some are more serious and last longer. Many studies have been published regarding hospital admission due to ADRs and it has been estimated that 2.9% to 5.6% of all hospital admissions are due to ADRs and 35% of the hospitalized patients experience an ADR during their hospital stay. Thus ADRs increase not only morbidity and mortality, but also add to the overall healthcare cost. In the present study a total of 1125 patients data were collected from six months study period. Out of 1125, 41 (3.64%) ADRs were identified. From among the 41patients, 22 (53.65%) were males and females were 19 (46.34%). This gender distribution percentage was compared with previous studies. The mean age of our study is 37.95±2.75 years and was compared with the previous similar studies. This study shows the high incidence of DHS 11 (26.8%), followed by drug induced acne form eruption 7 (17.2%). The study also showed that most ADRs occurred in age group of 21-30 years followed by 31-40 years. The incidence of ADRs more in male (53.65%) patients than female (46.34%) Patients. Most common ADRs were DHS (26.8%), Acne form eruption (17.2%), SJS (12.2%) and FDE (7.3%).Most common caused drugs were Antibiotics (31.7%), Antiepileptics (17%), Antituberculor drugs (12.1%) and Steroids (7.3%).
Neha Tabassum, Mohd Ilyas , Syedazizullah Ghori , Ashok Reddy and Mohd Mohiuddin 2
Deccan School of Pharmacy, Hyderabad-500 058, Andhra Pradesh, India.
18 June, 2014
28 August, 2014
15 November, 2014
01 February, 2015