DETERMINATION OF INORGANIC TOXICANTS IN NUTRACEUTICALS BY INDUCTIVELY COUPLED PLASMA MASS SPECTROSCOPYAbstract
Moringa oleifera and chywanprash are two main nutraceuticals used worldwide because of their large medicinal application. The quality of these nutraceutical products is in question, especially due to the inorganic contaminants like heavy metals. In the present study, six Moringa herbal powder and five chywanprash samples were collected in India and further analyzed for As, Cd, Hg, and Pb. All samples were microwave digested and analyzed by ICP-MS. In Moringa As, Cd, Hg and Pb were found in the range of 0.027-5.264 µg/mL, 0.014-0.039 µg/mL, 0.049-45.225 µg/mL and 0.323-12.487 µg/mL respectively. In chywanprash As, Cd, Hg and Pb were found in the range of 0.012-0.021 µg/mL, 0.004-0.029 µg/mL, 0.01-0.103 µg/mL and 0.06-0.171 µg/mL respectively. The concentration of these heavy metals were found to be more than the maximum permissible limit given by the WHO for herbal medicines. Hence strong regulatory guideline needs to be prepared to improve quality of nutraceuticals.
Ashwini Satpute and Astha Pandey *
School of Forensic Science, National Forensic Sciences University, Gandhinagar, Gujarat, India.
15 September 2020
29 May 2021
22 June 2021
01 September 2021