DEVELOPMENT AND EVALUATION OF FLASH RELEASE ORAL WAFER CONTAINING ANTIBIOTIC
AbstractIn the 21st century, human lifestyle has been faster than previous. People of this generation require faster results of each and everything which leads to change in lifestyle. Due to this immediatism invention of rapid release dosage forms are immerging in pharmaceutical market, from which Oral wafer is one of the dosage forms which provides rapid release of the drug. These oral wafers can be administered by oro-mucosal route which can be on the tongue, sublingually or buccal route. It disintegrates in saliva within 14 seconds and dissolution of 99% of drug in saliva has obtained within 60 seconds. There was total three challenges in this research. The antibiotic used in this research was BCS class II drug which leads to poor water solubility which may hamper the rapid action. Extremely bitter taste of drug was the second challenge and Incorporation of high dose in oral wafer was the third challenge. These all challenges have been conquered in this research.
Article Information
17
3555-3568
1488 KB
19
English
IJPSR
S. A. Ganguly *, M. K. Lohkare and R. N. Jadhav
Indrayani Institute of Pharmacy, Talegaon Dabhade, Pune, Maharashtra, India.
iipsohini@gmail.com
03 July 2024
23 August 2024
24 October 2024
10.13040/IJPSR.0975-8232.15(12).3555-68
01 December 2024
Download