DIURETIC ACTIVITY OF METHANOLIC RHIZOME EXTRACT OF PICRORRHIZA KURROA ROYLE EX. BENTH.Abstract
Kidneys are the excretory organs of our body that serves the important functions such as elimination of waste products, regulation of fluid volume and electrolyte content of the extracellular fluid. Picrorrhiza kurroa (Scrophulariaceae) is a small perennial herb growing in the hilly parts of the north-Western Himalayas region in India and Nepal. The objective of the present study was to evaluate and compare diuretic activity of Picrorrhiza kurroa royle ex. Benth with that of the standard. Two doses of the test extract i.e. 300mg.kg and 500mg.kg body weight orally are used to evaluate the diuretic activity. Furosemide (20mg/kg i.p.) was used as the standard drug to compare the test results. The test extract showed significant diuretic activity (p<0.05) which justify its use in ethnomedicine.
A. Rajani, M. Vishnu Vardhan Reddy , M. Madhuri , K. Hemamalini and M. Swathi
Sree Dattha Institute of Pharmacy, Sheriguda, Ibrahimpatnam, R.R. District, Andhra Pradesh, India
22 October, 2013
21 November, 2013
13 February, 2014