DRUG UTILIZATION TRENDS OF ORAL ANTI-DIABETIC AGENTS AMONG DIABETES MELLITUS TYPE 2 PATIENTS IN A TERTIARY CARE HOSPITALAbstract
Diabetes is a group of metabolic diseases and emerged as a major healthcare problem. According to the International Diabetes Federation (IDF), India has a large number of people suffering from diabetes, which will increase to almost 101 million by the year 2030. The pharmacotherapies of diabetes mellitus are diversified in their mechanism of action, safety profiles and tolerability. Drug utilization studies are important for the optimization of drug therapy. The present study aimed to evaluate the drug utilization pattern of anti-diabetic drugs in a tertiary care teaching hospital. It was a cross-sectional study, enrolled 255 patient’s prescriptions. Information was noted from prescriptions prescribed to the patients by a Doctor in prepared pro forma. It was found that combination therapy is predominant over monotherapy. The study has indicated metformin as the predominantly recommended oral anti-diabetic drug both as monotherapy and combination therapy. Metformin + glimepiride was the most commonly prescribed in combination therapy. The highest adverse drug reactions reported in our study are metformin + glimepiride which is different from other studies.
Pushp Raj Gour, Kavita Dhar Bagati *, S Balakrishnan and Neha Bhasin
Department of Pharmacology, School of Medical Sciences and Research Sharda University Greater Noida, Uttar Pradesh, India.
13 October 2020
11 February 2021
09 October 2021
01 November 2021