EFFECT OF PUTRANJIVA ROXBURGHII WALL. ON PHAGOCYTOSIS AND CHEMOTAXIS BY POLYMORPHONUCLEAR LEUKOCYTE CELLS (IN-VITRO STUDY)Abstract
Polymorphonuclear leukocytes or neutrophils are important components of host defense machinery. They are the first line of defense against invading microorganisms. In the present research work, ability of human neutrophils to phagocytose was studied in-vitro by exposing the polymorphonuclear leukocytes to Candida albicans and the phagocytic capacity was evaluated using aqueous extract of leaves powder of Putranjiva roxburghii Wall. The chemotactic activity that is the movement of polymorphonuclear leukocytes towards a chemical stimulant was studied in-vitro by placing polymorphonuclear leukocytes in presence of a chemotactic agent Zymosan using aqueous extract of leaves powder of Putranjiva roxburghii Wall.
Department of Chemistry, Ramnarain Ruia Autonomous College, Matunga Mumbai, Maharashtra, India.
18 January, 2018
19 September, 2018
22 September, 2018
01 October, 2018