EFFECT OF SOLANUM TORVUM SW. METHANOLIC EXTRACT ON IN-VITRO AND IN-VIVO MODELS OF INFLAMMATIONAbstract
The word inflammation comes from the latin word called “inflmmare” which means “To set on fire”. It is a complex biological process that is mediated by several chemicals and biological mediators like pollens, irritants, pathogens and damaged cells. The body’s inflammatory reaction destroys such chemical and biological mediators and gets rid of injured tissues. But in chronic state this inflammation seems to produce symptoms that are quite serious and may be life-threatening. Solanum torvum Sw. is a normal weed found in road side and abandoned field very often in Assam, but it’s berries are used by the Tiwa tribe of Morigaon district, Assam, to treat painful inflammation caused due to trauma or any kind of infection. It is quite common among the tribe to coat the inflamed area with fresh raw berry paste of Solanum torvum Sw. for 2 to 3 days, they take the bitter juice of berries as drink. The author have carried out both in-vitro and in-vivo experiment on the anti inflammatory properties of this berry methanolic extract. The study showed a strong efficacy of Solanum torvum Sw. berry extract in the bothmodels of inflammation in compared with standard drug. A preliminary phytochemical analysis was also conducted to make sure the presence of effective phytochemicals which have anti inflammatory properties.