EFFECT OF VITAMIN B12 SUPPLEMENT ON SERUM LEVELS OF VITAMIN B12 AND MEMORIZING ABILITY ON PRESCHOOL CHILDRENAbstract
This research aimed to analyze the effect of vitamin B12 supplementation on vitamin B12 serum level and memorizing ability of preschool children. A community – randomized controlled trial of 29 preschool children (4-6 year) was conducted for six months. Subjects were divided into two groups, treatment group (received 10 mcg of vitamin B12 daily syrup) and control group (placebo). Serum vitamin B12 and memory levels of children were measured before and after the intervention. Result of research was after 6 months of vitamin B12 on supplementation prevalence of vitamin B12 deficiency decreased in treatment group from 26.7% to 0.0%, while in the control group increased from 21.4% to 28.6%. The mean of increasing serum vitamin B12 was significantly different among those groups (148 ± 110.9 pg/ml in the treatment group and 3.7 ± 12.8 pg/mL in the control group). Memorizing ability affected by vitamin B12 supplementation for overall children with relative risk (RR) was 19.5. Reviews of this research imply the important result of vitamin B12 supplementation on improving vitamin B12 and memory levels of preschool children.
Z. Lubis *, Hardinsyah, S. Hidayat, F. Jala and Muhilal
Faculty of Public Health of University of North Sumatra, Medan, Indonesia.
12 January, 2018
05 June, 2018
13 July, 2018
01 October, 2018