EFFICACY OF TWO AYURVEDA REGIMEN IN MILD SCORPION STING: AN OPEN-LABEL, TWO-ARM, CLINICAL TRIALAbstract
Background: Scorpionism is an endemic and highly prevalent public health predicament causing severe cardio or neurotoxic effect. Ayurveda proposes a range of medicinal preparations (internal & external) in the management of Vrishchika Damsha (Scorpion sting). Among them, Hingwadi and Jeerakadi lepa are topical anti-inflammatory medications, and Bilwadi Gutika is a potent vishahara medicine (Alexeterics). Aims: To evaluate the comparative effect of Hingwadi Lepa against Jeerakadi Lepa with Bilwadi Gutika pana in the management of manda vrishchika damsha (mild scorpion sting). Methods: The present study adopted an open labelled two armed clinical trial of before and after the pilot study. It was conducted at a tertiary Ayurveda center with 30 subjects satisfying inclusion and diagnostic criteria. They were selected by convenience sampling method and divided randomly into two groups. Group I received Hingwadi lepa, and Group II was given Jeerakadi Lepa twice daily & Bilwadi Gutika pana (1gm) t.i.d. was administered orally in both groups for 7 days. Standard scoring of cardinal symptoms was used to measure the efficacy of treatment before and after treatment. Statistical analysis was done within the group by using student’s paired t-test and in between the groups by using an unpaired t-test. Results: The study showed highly significant improvement within the group in reducing the three cardinal symptoms with P<0.001. A significant result was obtained between the group with P<0.05. Conclusion: Hingwadi lepa is more effective when compared to Jeerakadi Lepa along with Bilwadi Gutika pana in mild scorpion sting.
T. K. Sanath *, Shrilata, A. Niranjan and A. K. Muraleedhran
Department of Agad Tantra, Faculty of Ayurveda, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh. India.
03 August 2020
06 September 2020
23 May 2021
01 August 2021