EMBLICA OFFICINALIS ENHANCES CARDIAC TISSUE REGENERATION IN TADPOLES OF THE FROG RANA CYANOPHLYCTIS (SCHNEIDER)Abstract
Emblica officinalis and its derivative (Ascorbic acid) have profound effect on development and regeneration and are widely used in the Indian System of medicine for the treatment of different type of disease. Here, we discussed the comprehensive account of the effect of aqueous extract of the fruit of E.officinalis with special reference to cardiac tissue regeneration in frog tadpoles. E.officinalis was found to be a good model to accelerate regeneration ability of infracted cardiac cells which further give rise to intact cardiac part (intact ventricle part) in all mode of experiment employed i.e insitu (in vivo), in transplantation setup and in culture medium. The most spectacular case was rhythmic beating of implanted cardiac tissue at ectopic site of tail of E.officinalis treated tadpoles. The E.officinalis supplemented cultures were also appeared to be a suitable for investigating the changes occurred during regeneration and differentiation of cardiac muscles.
Govind Kumar Gupta* and O.P Jangir
Department of Biotechnology, IASE Deemed University, Sardarshahr, Rajasthan, India
27 February, 2015
15 May, 2015
30 June, 2015
01 September, 2015