ESTIMATION OF LORNOXICAM IN TABLET DOSAGE FORM BY UV SPECTROPHOTOMETRIC METHODAbstract
Lornoxicam (chlortenoxicam) is a non steroidal anti- inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory and antipyretic properties. It is available in oral and parental dosage formulation. Lornoxicam is a Yellow or slightly yellow powder. It is slightly soluble in water, soluble in hydrochloric acid, slightly soluble in methanol. A simple spectrophotometric method was developed for the determination of lornoxicam in pharmaceutical tablet dosage form. Lornoxicam exhibiting λ max at 380 nm in mobile phase (phosphate buffer: methanol) in ratio of 50:50 and obeyed linearity in the concentration range of 1-20mcg. The proposed method was statistically validated.
Bhupendra Singh*, Geetanjali Saini, Devendra N Naath Sharma, Saumendu Deb Roy and Nishant Gautam
Abhilashi College of Pharmacy, Tanda, Ner Chowk, Mandi, H.P., India
04 August, 2010
10 November, 2010
26 December, 2010