EVALUATION OF ADULTERATION OF HERBAL MEDICINE USED FOR TREATMENT OF ERECTILE DYSFUNCTION IN NAIROBI COUNTY, KENYA:Abstract
In the recent past, adulteration of herbal products has increased rapidly, and today it is a global problem. Synthetic Phosphodiesterase type 5 inhibitors are the main adulterants in herbal medicine used for erectile dysfunction. The present study evaluated the herbal medicines used as sex enhancers in Nairobi County, Kenya, for adulteration with Phosphodiesterase type 5 inhibitors (sildenafil, tadalafil, and vardenafil). The products were purchased from health stores in Nairobi County. Samples were screened for adulteration with sildenafil, tadalafil, and vardenafil using HPTLC. Quantification was done by integration of sample chromatograms against standard chromatograms. The samples analyzed, 33.5% were adulterated. All the adulterated samples were imported, and none of the locally manufactured samples were found adulterated. The study revealed that samples from China/Hong Kong had the largest number 14 (53.85%) of the adulterated samples. These findings were in agreement with previous studies. A number of samples (32.5%) samples studied were adulterated. Sixty percent (60%) of adulterated samples contained sildenafil, while a few samples had either tadalafil, vardenafil or the combination.
S. W. A. Sifuma *, J. W. Mwangi, P. C. Mutai, D. B. Ongarora and N. M. Njuguna
Department of Pharmacology and Pharmacognosy, School of Pharmacy, University of Nairobi, P.O Box 19676-00202, Nairobi, Kenya.
11 August 2021
30 September 2021
28 March 2022
01 May 2022