EVALUATION OF ANALGESIC ACTIVITY OF MOMORDICA DIOICA ROXB. WILLD FRUIT PULP
AbstractIn the present study Momordica dioica Roxb willd (Cucurbitaceae) fruit pulp was successively extracted with petroleum ether, ethyl acetate and methanol. All extracts were vacuum dried to yield the respective extracts. All extracts were evaluated by non-narcotic models like acetic acid induced writhing syndrome test and narcotic models like hot plate for its analgesic activity in doses of 50 mg/kg and 100 mg/kg in mice body wt. All petroleum ether, ethyl acetate and methanol extracts gives significant exhibited analgesic activity in acetic acid induced writhing syndrome and hot plate when compared to the vehicle treated control group. But among them petroleum ether and methanol extract gives more significant exhibited analgesic activity than ethyl acetate extract.
Article Information
8
53-56
355 kB
1112
English
IJPSR
M. S. Rakh *, S. R. Chaudhari
Department of Pharmacognosy, Amrutvahini College of Pharmacy, Sangamner, Dist. Ahmednagar, Maharashtra, India
maharudra_rakh2001@yahoo.co.in
23 May, 2010
14 July, 2010
21 August, 2010
http://dx.doi.org/10.13040/IJPSR.0975-8232.1(9-S).53-56
15 September, 2010
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