EVALUATION OF ANALGESIC ACTIVITY OF MOMORDICA DIOICA ROXB. WILLD FRUIT PULPAbstract
In the present study Momordica dioica Roxb willd (Cucurbitaceae) fruit pulp was successively extracted with petroleum ether, ethyl acetate and methanol. All extracts were vacuum dried to yield the respective extracts. All extracts were evaluated by non-narcotic models like acetic acid induced writhing syndrome test and narcotic models like hot plate for its analgesic activity in doses of 50 mg/kg and 100 mg/kg in mice body wt. All petroleum ether, ethyl acetate and methanol extracts gives significant exhibited analgesic activity in acetic acid induced writhing syndrome and hot plate when compared to the vehicle treated control group. But among them petroleum ether and methanol extract gives more significant exhibited analgesic activity than ethyl acetate extract.
M. S. Rakh *, S. R. Chaudhari
Department of Pharmacognosy, Amrutvahini College of Pharmacy, Sangamner, Dist. Ahmednagar, Maharashtra, India
23 May, 2010
14 July, 2010
21 August, 2010
15 September, 2010