EVALUATION OF ANALGESIC ACTIVITY OF SOME NOVEL SUBSTITUTED L-ARGININE ANALOGUES
AbstractA series of novel L-arginine analogues were synthesized characterized and screened for analgesic activity by acetic acid induced analgesia model. The purity of the synthesized compounds has been characterized by various analytical techniques such as UV, FTIR and TLC. The synthesized compounds were evaluated for analgesic activity by acetic acid induced analgesia in mice using paracetamol as the standard drug for comparing the test results. The study concluded that the compound 1, 2, 3 and 4 were found to exhibit significant anti-pyretic action.
Article Information
56
2038-2040
394KB
1199
English
IJPSR
S. K. Arifa Begum, M. Madhuri, A.Rajani and K. Hemamalini*
Associate Professor & HOD, Department of pharmacology, Teegala Ram Reddy College of Pharmacy, Meerpet, Hyderabad, AP, India
rajani_adepu85@yahoo.com
19 December, 2013
10 January, 2014
16 April, 2014
http://dx.doi.org/10.13040/IJPSR.0975-8232.5(5).2038-40
01, May 2014
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