EVALUATION OF ANTHELMINTIC ACTIVITY OF THE METHANOLIC EXTRACT OF AMORPHOPHALLUS PAEONIIFOLIUS TUBERAbstract
Methanolic extracts of the tuber of Amorphophallus paeoniifolius were investigated for its antihelmintic activity against Pheretima posthuma and Tubifex tubifex. The extract with the concentrations of 25, 50 and 100 mg/ml were tested in the bioassay, which involved determination of time of paralysis and time of death of the worms. The extract exhibited significant antihelmintic activity at highest concentration of 100 mg/ml. Piperazine citrate (10 mg/ml) was included as standard reference and distilled water as control. The extracts were found not only to paralyze (Vermifuge) but also to kill the earthworms (Vermicidal).
Yadu Nandan Dey* and Ajoy Kumar Ghosh
Central Council for Research in Ayurveda and Siddha, Janakpuri, New Delhi, India
29 August, 2010
13 October, 2010
24 October, 2010
01 November, 2010