EVALUATION OF ANTI-OXIDANT, ANTI-INFLAMMATORY AND CYTOTOXICITY POTENTIAL OF HEMIGRAPHIS COLORATA
AbstractPlants have been used as a source of natural products for various therapeutic processes from a long time. The proposed work illustrates the study of the importance of natural products in terms in-vitro approaches. On account of this study the phytochemical constituents of various extracts of Hemigraphis colorata (Blume) are evaluated. The plant was traditionally known for its wound healing activities. Crude plant extract was prepared by percolation method using a Soxhlet apparatus. The solvents used were Hexane, Chloroform, Acetone and Ethanol .The in-vitro antioxidant capacity was analysed through DPPH and reducing power assays. Anti-inflammatory properties of various extracts from the whole plant are analyzed through human RBC membrane stabilisation method. The anti-oxidant and anti-inflammatory activities were more for the ethanolic extracts of Hemigraphis colorata when compared to acetone, chloroform and hexane extracts.The in-vitro cytotoxicity analysis of ethanolic extract was also carried out in the present study using trypan blue method
Article Information
25
3477-3483
579KB
2425
English
IJPSR
T.T. Akhil* and Punieethaa Prabhu
Department of Biotechnology, K.S. Rangasamy College of Technology, Tiruchengode- 637 215, Nammakkal, Tamil Nadu, India
akhiltthilak@gmail.com
25 April, 2013
12 June, 2013
18 August, 2013
http://dx.doi.org/10.13040/IJPSR.0975-8232.4(9).3477-83
01 September, 2013
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