EVALUATION OF ANTIMICROBIAL ACTIVITY OF PLANT EXTRACTSAbstract
The objective of this study was to evaluate the possible antimicrobial properties of water, methanol, chloroform and Petroleum ether extracts of leaves of different Indian medicinal plants including Mangifera indica Linn, Ixora parviflora Vahl, Psydium guajava Linn, Calotropis procera Ait. The extracts were investigated individually for in vitro antibacterial activity by cup plate (well diffusion) method against nine pathogenic bacteria cultures. Of all the plants investigated for antimicrobial potential, the leaf extracts of Psydium guajava showed high antimicrobial activity against the tested microorganisms. Methanolic leaf extract of Psydium guajava was found to exhibit highest antimicrobial activity. Water leaf extracts of Mangifera. Indica and Ixora parviflora did not show antimicrobial activity. Phenolic content of Psydium guajava could contribute towards its antibacterial activity. The antibacterial activities of the investigated plants could make it useful in microbial infections.
Department of Pharmaceutical Chemistry, S.V.K.M’S, Dr. Bhanuben Nanavati College of Pharmacy, Mithibhai College Campus, V.M. Road. Vile Parle- (W), Mumbai - 400 056, India
05 August, 2014
27 October, 2014
15 December, 2014
01 April, 2015