EVALUATION OF ANTIMICROBIAL POTENTIAL OF ELAEOCARPUS SERRATUS L.Abstract
The in vitro antimicrobial activity of acetone, methanol and water extracts of leaf, stem bark and fruit of Elaeocarpus serratus L. (Elaeocarpaceae) was examined against four bacterial species (Shigella sonnei, Salmonella typhi, Staphylococcus aureus and Klebsiella pneumoniae) and a fungal species (Candida albicans) using the agar well diffusion method. Phytochemical screening was carried out for phenols, flavonoids and tannins. Results showed that the plant extracts exhibited a dose-dependent inhibition of microorganisms. The acetone and methanol extracts of leaf and stem bark of E. serratus displayed maximum antibacterial activity against all the bacterial species studied. The plant extracts also displayed high antifungal activity against Candida albicans especially, the acetone extract was found to be more active antifungal. Generally, the lower concentrations of the extracts were susceptible to the fungal pathogen. E. serratus extracts contained phenols, flavonoids and tannins at varying levels. The ability of the crude extracts of the test plant to inhibit the growth of bacteria and fungi is an indication of its broad spectrum antimicrobial potential which may be employed in the management of microbial infections.
Indhiramuthu Jayashree*, DH. Geetha and M. Rajeswari
PG and Research Department of Botany, Vellalar College for Women, Erode-12, Tamil Nadu, India
28 January, 2014
29 March, 2014
17 June, 2014
01 August, 2014