EVALUATION OF ANTIOXIDANT AND ANTI-ULCER ACTIVITY OF SMILAX PERFOLIATA LINN.Abstract
The leaves and fruits of Smilax perfoliata are traditionally used for treatment of various ailments such as rheumatism, lumbago, nourishing the functions of spleen, stomach, muscle and bone. The intent of the present study was to evaluate the antioxidant and anti-ulcer activity of ethanolic leaves and fruits extract of Smilax perfoliata Linn in albino rats. Gastric ulcers were induced by employing pylorus ligation method of induction. The anti-ulcer activity was analyzed by estimation of free acidity and the total acidity. The antioxidant potential was analyzed by method of DPPH free radical scavenging activity. The results obtained showed that the leaves and fruits of Smilax perfoliata possess antioxidant potential and are capable in the ministration of gastric ulcers.
S. Abdul Arsalan *, S. B. Mahmood, S. Rashid Ali, A. Begum, Md. Ismail, Md. Akbar Siddiq
Sultan ul Uloom college of Pharmacy, Mount Pleasant, Hyderabad, Adhra Pradesh, India
15 October, 2014
16 December, 2014
08 February, 2015
01 June, 2015