EVALUATION OF ANTIOXIDANT AND ANTIMICROBIAL ACTIVITY OF A MEDICINAL PLANT HYDROCOTYLE SIBTHORPIODES LAM., GROWN IN NE INDIAAbstract
The present study was conducted to evaluate the antioxidant and antibacterial activities of methanol and aqueous extracts of whole plant of Hydrocotyle sibthorpiodes Lam. Antioxidant activity was measured using reducing power, hydrogen peroxide and 2, 2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging assays. The antioxidant activity was expressed as percentage (%) of DPPH and H2O2 radicals’ inhibition and IC50 value. Methanolic extract of the whole plant showed highest antioxidant activity each for DPPH (85.80±0.29) as well as H2O2 (64.7±0.173) compared to the aqueous extract with an IC50 value of 50.1µg/ml and 60.2 µg/ml respectively. Antibacterial activity was tested against two pathogenic strains by agar well diffusion method. The extracts were found to exert low to moderate antibacterial activity compared to Chloramphenicol which was taken as standard.