EVALUATION OF IN-VITRO ANTI-OXIDANT ACTIVITY OF SOME SYNTHESIZED NOVEL L-ARGININE ANALOGUES
AbstractA series of novel L-arginine analogues were synthesized and screened for in-vitro anti-oxidant activity by Nitric oxide (NO) scavenging and 1-1-diphenyl-2-picrylhydrazyl (DPPH) scavenging methods. The purity of the synthesized compounds has been characterized by various analytical techniques such as UV, FTIR and TLC. The synthesized compounds were evaluated for in-vitro anti-oxidant activity by NO scavenging and DPPH scavenging methods. The study concluded that the compounds4, 5, 6, 7, 8, 10, 11 exhibited very significant anti-oxidant action in NO scavenging method and compounds 4, 6, 7, 8, 10, 11 has exhibited significant anti-oxidant activity in DPPH scavenging method when compared with that of the standard Ascorbic acid.
Article Information
58
2051-2054
424KB
1159
English
IJPSR
S. K. Arifa Begum , M.Madhuri , A.Rajani and K. Hemamalini *
Associate Professor & HOD, Department of pharmacology, Teegala Ram Reddy College of Pharmacy, Meerpet, Hyderabad
rajani_adepu85@yahoo.com
19 November, 2013
11 January, 2014
18 April, 2014
http://dx.doi.org/10.13040/IJPSR.0975-8232.5(5).2051-54
01, May 2014
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