EVALUATION OF MIXTURES OF AQUEOUS EXTRACT OF PSEUDOCEDRELA KOTSCHYI AND BOSWELLIA DALZEILII AS INTERACTING PRODUCTS IN REGULATION OF PHAGOCYTOSIS AND LYMPHOCYTES PROLIFERATIONAbstract
The current study aimed to test the effect of the aqueous extract of Boswellia dalzeilii and Pseudecedrela kotschyi using three different mixing ratios (B. dalzeilii:P. kotschyi) 3:1, 2:2, and 1:3. The assays concerned the study of the interactions in the modulation of phagocytic index, nitric oxide production, lysosomal enzymes and myeloperoxydase activity in macrophages and regulation of lymphocytes proliferation. The study results showed that the extracts of these plants exhibited antagonistic effects in the phagocytic index and production of NO while they produced synergetic effects in the stimulation of MPO-dependent activity and lymphocytes proliferation. Antagonistic effects were produced in the ratios 3:1 and 2:2 and synergetic properties in the ratios 1:3 for the stimulation of the activities of the lysosomal enzymes. These results look quite interesting and important and merit further investigations to support the present findings.
Oumar Mahamat *, Tume Christopher, Kamtchueng Monique Odette and Kamanyi Albert
Department of Biological Sciences, Faculty of Science, University of Bamenda, Cameroon
07 October, 2015
13 February, 2016
20 February, 2016
01 April, 2016