EVALUATION OF N-(6-CHLOROBENZOTHIAZOL-2-YL)-2-(SUBSTITUTEDAMINO)ACETAMIDE FOR ITS ANTI-BACTERIAL ACTIVITYAbstract
In the present study, a series of some novel benzothaizole derivatives (BZT 1-10) were screened for their antibacterial activity against S. typhi, S. dysenterae, E. coli, S.aureus and B. subtlis employing Disc Diffusion method and taking Agar as culture media. Streptomycin (25µg/ml) was used as a standard drug. The solvent, DMSO used for the preparation of compounds did not show inhibition against the tested organisms which serves as the negative control. After evaluation of results, most of the derivatives have shown efficient diameter of zone of inhibition as compared to control as well as standard which confirms the promising antibacterial activity of the benzothaizole derivatives.
Pranav Prabhat*, Sreemoy Kanti Das, Kausar Shafaat and J.P. Anand
Faculty of Pharmacy, S. Sinha College, Aurangabad- 824 102, Bihar, India
21 April, 2012
18 June, 2012
27 July, 2012
01 August, 2012