EVALUATION OF SAFETY PROFILE OF ANTI HYPERTENSIVE DRUGS WITH THE EFFECT OF PATIENT COUNSELINGAbstract
Objective: To establish does response relationship to the hypertensive patients and ensure safety profile of drugs through counseling of patients.
Method: Patients who have suffered by secondary hypertension with blood pressure range of above 145-170/100-110 mmHg are selected and divided in two groups. First group of patients to administer for Nifedipine 5mg and furosemide 40mg administered for second group patients by orally .Every 30minits of after 4hrs blood pressure monitored and compliance about disease and drugs from patients are collected and recorded. Finally statistically analyzed safety and does response of the drugs.
Discussion: 30% of patients were found to be 111-115/90-95 mmHg after treated with nifedipine and 27.5%of patients blood pressure reduced into 116-120/95-100mmHg for after administration of furosemide.
Conclusion: In this study it was found that nifedipine is effective in the management of hypertension in terms of efficacy than furosemide. We should recommend this regimen for treatment of hypertensive patients in RMMC&H.
K. Seiyadu Ibrahim* and Jesima Begum
Clinical Pharmacist, King Khalid University Hospital, King Saud University, Riyadh, Kingdom of Saudi Arabia
25 August, 2010
28 November, 2010
26 December, 2010