EVALUATION OF SELECTED MEDICINAL PLANTS FOR ANTIUROLITHIATIC ACTIVITYAbstract
The main aim of our study is to evaluate the antiurolithiatic activity of pomegranate (punica granatum, Family: Puniaceae) and garlic (Allium sativum, Family: Liliaceae). For this, we have subjected the seeds of pomegranate and garlic bulbs to maceration using 95% of ethanol, ethyl acetate, petroleum ether and water at a ratio of 1:4 for 24 hours, followed by reflux over a water bath for 3 hours and the obtained extract was concentrated under vacuum. The prepared extracts were then subjected to titrimetry and colorimetry for the estimation of calcium and phosphate respectively. By comparing the result of different extracts, we have found that ethanol extract of garlic has showed better result in inhibiting precipitation of calcium and phosphate. But individual isolation and further studies are to be carried out to confirm this activity.
P. Sai Sindu*, M. Aparna, B. Sravani, M. Kranthi and T. Ratna Maheswari
Siddharth Institute of Pharmacy, Kantepudi (v), Guntur (dist), Andhra Pradesh, India
24 August, 2012
25 September, 2012
28 November, 2012
01 December, 2012