EVALUATION OF THE ANALGESIC EFFECT OF THE COMBINATION OF INTRA-CANAL ANALGESICS AND CRYOTHERAPY IN CONTROLLING PAIN DURING NON-SURGICAL ROOT CANAL TREATMENT – A RANDOMIZED CONTROL STUDY

Aim: Patients often experience varying degrees of pain during or after root canal therapy. This study aimed to the analgesic effect of the combination of intra-canal analgesics and Cryotherapy in controlling pain during non-surgical root canal treatment. Methodology: This Double-blind, parallel, randomized clinical trial included 76 patients (42 men and 34 women) within the age range of 18-65 years with maxillary or mandibular premolars having symptomatic irreversible pulpitis or symptomatic apical periodontitis. Patients were divided into two groups: Group 1 received precooled analgesic solution for irrigation during root canal treatment, Group 2 used Ketorol DT tablets during and post root canal treatment. Pain levels were assessed using the visual analogue scale (VAS) before treatment, during treatment, and at 2, 6, 12, 24 hours inter and post-treatment. Statistical analysis included mean, standard deviation, Mann Whitney U test and Wilcoxon Signed Rank Post Hoc tests. Results: There is a significant decrease in the levels of pain in the patients at 6 hours post cleaning and shaping across both the groups. It is also observed that the decrease in the post operative pain at 6 hours interval post cleaning and shaping is significantly higher in the precooled analgesic group when compared to the oral medication group. Conclusion: Enhanced analgesic effect of pre cooled analgesic is effective in reduction of interappointment and post-operative endodontic pain.