EVALUATION OF WOUND HEALING ACTIVITY OF CROSSANDRA INFUNDIBULIFORMIS FLOWER EXTRACT ON ALBINO RATSAbstract
Crossandra infundibuliformis belonging to family Acanthaceae is well known medicinal plant in various region of India. This plant is one of the most chosen variety for folk medicine. Flower extract used in various conditions like fever, headache, aperitif, pain etc. Present study is concern mainly with evaluation of wound healing activity of flower ethanolic extract in Wistar rats using excision wound model in the form of ointment using two concentrations (2 and 4%w/w ointment) of flower extract in simple ointment base. Both concentration of ethanolic extract showed significant response in both the wound type tested when compared with control group. 4% w/w concentration has showed better significant value than the standard drug. Nitrofurazone ointment (0.2%w/w) was used as standard drug.
Rohit Gundamaraju* and T. Mohan Verma
Department of Pharmacolgy, Malla Reddy Institute of Pharmaceutical Sciences 1, Maisammaguda, Dhulapally (Post via Hakimpet), Secunderabad (500014), Andhra Pradesh, India
02 August, 2012
21 October, 2012
31 October, 2012