EXHAUSTIVE REVIEW ON THERAPEUTICAL ROLE OF SOME PHYTOCONSTITUENTS AND THEIR CHEMICAL ALTERATIONAbstract
Introduction: Therapeutic agent must be compatible with its target. Their multiple interaction produces diversified therapeutic action. Chemical exploration of phytoconstituents unravels bio–interaction and strategic engineering of molecules generates wonderful leads in therapeutics. Method: The source of information has been accessed through multiple research and review article of peered journals. The logical mechanics has been putted to churn the spread about phyto therapeutics of natural and its semi–synthetic derivatives. Result: For developing and designing a receptor/target compatible structure, chemical diversity of plants provides very good source to have a potent and effective therapeutic agent. Study of natural chemical templates helps not only to understand bio–mechanism but also creates a different approach of treatment. This review targets different diseases with natural compounds with enlighting the semi–synthetic analogues study of some of them. Exploring the chemistry/various character of molecule may provide a better fit model with minimal or no side effect. Discussion: On the basis of data processed phytotherapeutics may be explored upfront in pharmaceutical industry. These phyto magical entities presenting the mechanism upto depth of protein, DNA and genetic moulding. In future there will be more research ground in this area producing novel and better alternative for treatment with minimal toxic effects.