FORMULATION AND EVALUATION OF ANTI-AGING CREAM USING BANANA PEEL EXTRACTAbstract
Topical formulations may contribute to the reduction of oxidative stress in the skin. Banana peel is a fruit waste with antioxidant activity that is not yet included in a topical formulation. The aim of this study was to evaluate the antioxidant and anti-aging activity of a cream formulation containing a lyophilized extract of banana peel. The banana peel was extracted with ethanol, and a cream formulation containing 1% of the resulting extract was prepared. The total phenolic content (TPC), total flavonoid content (TFC), antioxidant and anti-aging activity of both extract and formulation were investigated. DPPH (2, 2-Diphenyl-1-picrylhydrazyl) free radical scavenging, ABTS (2, 2′-Azinobis (3-ethylbenzotrazole-6-sulfonate) cation radical scavenging, FRAP (Iron ion reduction) and CUPRAC (copper ion reduction) methods were used for antioxidant effect. For the anti-aging effect, elastase enzyme inhibitory activity was studied. The banana peel extract had a high antioxidant and anti-aging effect compared to the standards. Although the extract was added 1% in the cream, the cream showed antioxidant and anti-aging effects of about 80% of the extract. TPC and TFC findings also showed that this result due to phenolic and flavonoid compounds. It is possible to suggest that this formulation has the potential of antioxidant and anti-aging for topical use.
F. Uckaya * and M. Uckaya
Department of Nursing *, Faculty of Health Science, Alanya Alaaddin Keykubat University, Antalya, Turkey.
08 February 2021
12 June 2021
21 June 2021
01 January 2022