FORMULATION AND EVALUATION OF ANTIBACTERIAL HERBAL MOUTHWASH AGAINST ORAL DISORDERS
AbstractThe current study aims to develop and evaluate herbal mouthwash and ascertain its effectiveness against microbes. Conventionally herbal mouthwashes are used as a disinfectant to lessen the presence of microbes in the oral cavity. Herbal mouthwashes act as a preventative agent for bleeding gums, decoloring teeth, and killing off bad breath germs. The herbal mouthwashes also have inherent benefits of plaque control and inflammation. The formulated mouthwash was prepared using herbs and the extract was extracted by hot water extraction method. Additional analysis of the Phyto ingredients was done where the flavonoid content and phenolic content was estimated as 41.71µg/ml and 76.25µg/ml, respectively and the in-vitro antibacterial assay was performed against Streptococcus mutans and Streptococcus salivarius and the zone of inhibition was calculated as 18mm and 22 mm at the highest concentration. The results indicated that the mouthwash exhibits effective antibacterial qualities. These solutions can be used for various things, including reducing the growth of germs in the oral cavity and for their analgesic, anti-inflammatory, or antifungal effects.
Article Information
19
5725-5733
1196 KB
604
English
IJPSR
M. Govardhan, B. Hemanth, M. Ricwin, G. K. Yuvan Shankar, K. Yuvaraj and T. P. Karunya *
Department of Biotechnology, Vel Tech High Tech Dr. Rangarajan Dr. Sakunthala Engineering College, Chennai, Tamil Nadu, India.
karunya.tp17@gmail.com
17 April 2023
24 July 2023
28 July 2023
10.13040/IJPSR.0975-8232.14(12).5725-33
01 December 2023