FORMULATION AND EVALUATION OF HERBAL ANTIOXIDANT GEL
AbstractIntroduction: Herbal drugs have great growth potential in the global market. Natural product research continues to explore traditional medicines to develop new novel drugs. The present study aimed to investigate antioxidant potential of gel formulated with Punica granatum peel extract, Glycyrrhiza glabra root extract and Citrus sinensis peel extract. Method and Materials: Different gels were formulated by varying the concentration of the extracts and evaluation was done. The formulated gel was compared for antioxidant activity with standard marketed preparation. Results: The prepared formulations showed satisfactory rheological characteristics, release behavior, appearance, pH, and spreadability. The optimized gel formulation showed excellent antioxidant activity. The IC50 value of gel was 43.74 μg/ml, and that of marketed preparation was 51.15 μg/ml, which shows good antioxidant property of gel. Conclusion: The formulated 5% gel formulation showed good antioxidant activity when compared to the marketed preparation. Thus, the present investigation revealed that the developed gel formulation has potential antioxidant activity.
Article Information
47
3076-3083
916 KB
586
English
IJPSR
Samruddhi R. Nale *, Varsha M. Jadhav and Vilasrao J. Kadam
Department of Quality Assurance, Bharati Vidyapeeth’s College of Pharmacy, C.B.D. Belapur, Thane, Navi Mumbai, Maharashtra, India.
samruddhinale2296@gmail.com
19 October 2022
09 January 2023
30 April 2023
10.13040/IJPSR.0975-8232.14(6).3076-83
01 June 2023
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