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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

IJPSR is indexed with Embase

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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FORMULATION AND EVALUATION OF HYDRALAZINE HYDROCHLORIDE BUCCAL FILMS BY SOLVENT CASTING METHOD USING DIFFERENT POLYMERS FOR THE MANAGEMENT OF HYPERTENSION

Abstract

The main aim of the study was to formulate the buccal films of most satisfactory formulation by in-vitro evaluation. The present investigation was done to formulate Hydralazine hydrochloride with an objective to improve therapeutic efficacy, Patient compliance. Hydralazine hydrochloride buccal films were developed by solvent casting method. Formulation H2, P4, S8, was best fitted to the in-vitro release studies and zero order release was observed.

Article Information

24

3328-3333

588

1248

2

English

IJPSR

S. Muthukumar * and R. S. Ganapathy

Faculty of Pharmacy, Karpagam Academy of Higher Education, Coimbatore, Tamil Nadu, India.

pharmmuthu@gmail.com

19 November, 2017

24 January, 2018

06 February, 2018

10.13040/IJPSR.0975-8232.9(8).3328-33

01 August, 2018

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