FORMULATION AND EVALUATION OF NOVEL ANTIAGING CREAM CONTAINING RAMBUTAN FRUITS EXTRACTAbstract
Skin aging is a complex process induced by constant exposure to ultraviolet (UV) irradiation and damages human skin. Rambutan (Nephelium lappaceum), a delicious tropical fruit that grow in Malaysia and spread widely in most Southeast Asian countries, have strong antioxidants properties due to the presence of ellagic acid, corilagin, geraniin, β-carotene and vitamin C. These compounds scavenge the free radical and thereby protect the skin against oxidative damage. The aim of the present study is to formulate and evaluate an antiaging cream containing Rambutan fruits extract. The SMEP, SMEF, CMEP and CMEF produced significant antioxidant activities and tyrosinase inhibition with low IC50 values. All the four extracts were formulated into an antiaging cream and evaluated. The results showed that the formulated antiaging creams and its ingredients were consistent in quality and can be easily used. From the above results, it is concluded that the formulation containing SMEF and CMEF are safe and usable for the skin. The present results demonstrate that the Rambutan fruits extracts has a good potential for cosmetic product development.
Mahendran Sekar *, Pavitra Sivalinggam and Afzan Mahmad
Faculty of Pharmacy and Health Sciences, Universiti Kuala Lumpur, Royal College of Medicine Perak, Ipoh, Malaysia.
01 September, 2016
17 November, 2016
01 December, 2016
01 March, 2017