FORMULATION AND EVALUATION OF POLY-HERBAL ANTI-DIABETIC FAST-DISSOLVING TABLET FROM HOME REMEDY AND COMPARISON WITH MARKETED METFORMIN TABLETAbstract
The current study’s purpose was to develop and test a multi-herbal anti-diabetic quick-dissolving tablet compared to a commercially available metformin tablet. The multi-herbal anti-diabetic tablet contains natural medicines with anti-diabetic properties, such as Curcuma longa, Cinnamomum zeylanicum, Zingiber officinale, and Trigonella foenumgraecum. This mixture contains the botanical extracts Curcuma longa, Cinnamomum zeylanicum, Zingiber officinale, and Trigonella foenumgraecum. MCC is employed as a diluent and sodium saccharin as a sweetening agent in the tablet formulation to attain this purpose. In the formulation of tablets, superdisintegrants such as crospovidone, sodium starch glycolate (SSG), and a blend of crospovidone and sodium starch glycolate were used to improve dissolve rate and disintegration. Weight variation, drug content uniformity, hardness, friability, wetting time, in-vitro dispersion time and in-vitro drug release investigations were performed on the tablets. Every parameter’s evaluation results for the poly-herbal anti-diabetic pill were within acceptable boundaries. The thickness, hardness, weight fluctuation, friability and in-vitro drug release investigations of the poly-herbal anti-diabetic tablet were all found to be within acceptable ranges.
Chandrashekhar Patil *, Deepak Somavanshi, Ganesh Sonawane, Kajal Pansare and Mohammed Saad
Divine College of Pharmacy, Satana, Maharashtra, India.
10 September 2022
20 October 2022
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01 May 2023