FORMULATION AND EVALUATION OF TOOTHPASTE CONTAINING COMBINATION OF ALOE AND SODIUM CHLORIDEAbstract
The formulation and evaluation of toothpaste contain Aloe vera along with the combination of sodium chloride. Aloe vera shows a number of uses either internally or externally, and the number of uses also increases as the research going on. In this formulation, we tried to find out the antimicrobial activity of Aloe vera in toothpaste formulation, for the said purpose we use S. aureus culture. After designing the batches in software Design Expert® 10, the batches were formulated and evaluated. At the end of work, we found that the prepared toothpaste shows considerable zone of inhibition which concludes its antimicrobial activity. The formulation also shows sufficient foaming power for its cleansing action. The observed results were found to significant concerning the chosen cubic model in software Design Expert® 10. Thus from the collected results, we concluded that the toothpaste containing a combination of Aloe and sodium chloride possesses antimicrobial activity, but for its practical use its necessary to determine its effect on oral cavities and probable side effects after its long tern use of its oral application as its future scope. The present work provides hint for those who prefer herbal formulations.
P. L. Phalke *, T. G. Rukari and A. S. Jadhav
VJSM’s Vishal Institute of Pharmaceutical Education and Research, Ale, Junnar, Pune, Maharashtra, India.
10 July 2018
10 September 2018
15 September 2018
01 March 2019