FORMULATION OF HERBAL GEL FOR POTENTIAL ANTIBACTERIAL ACTIVITY AGAINST PSEUDOMONAS AERUGENOSA
AbstractThe present work deals with the formulation of containing aqueous extract of Tectona grandis (Teak) Leaves and prepared formulation against some Gram-positive and Gram-negative bacteria. The antibacterial activity of various T. grandis leaves extracts was measured by determining minimum inhibitory concentration (MIC) by cube dilution method and zone of inhibition by disc diffusion method against P. aeruginosa, Aqueous T. grandis Leaves extracts exhibited comparatively higher antibacterial potential in comparison with other extracts. All the prepared herbal formulations were subjected to antibacterial study by determining the zone of inhibition by disc diffusion. Herbal formulations containing gel aqueous exhibited better zones of inhibition against P. aeruginosa in comparison with others. This type of bacteria (germ) is found commonly in the environment, like in soil and water. From the results of this study, it can be concluded that herbal formulations containing gel aqueous T. grandis leave extract are found suitable for use against bacterial infections in the form of topical gels or another suitable dosage form.
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