FORMULATION OF OIL CONTAINING PLUCHEA LANCEOLATA EXTRACT OBTAINED THROUGH DIFFERENT ORGANIC SOLVENTS AND EVALUATION OF ITS ANTI-INFLAMMATORY ACTIVITY BY TOPICAL APPLICATIONAbstract
Pluchea lanceolata has been used in massage oil as well as in traditional ayurveda as a potent pain reliever. The traditional Method of obtaining oil is simply based on taking water as the medium for extraction. The water extract obtained is then boiled with oil, till the water is completely evaporated. Here, our aim is to replace water by different organic solvents and obtain oil which has much better efficacy than the traditionally extracted oil. The idea here is to obtain more efficacious oil than the marketed sample which is majorly extracted using water as solvent. Here, the different organic solvents used are methanol, ethanol, petroleum ether and chloroform. The oil obtained was checked for its anti-inflammatory activity with the carrageenan induced rat paw edema. The prepared oil was compared with the marketed sample of mahanarayan oil. The ethanolic extract has showed to be having high extract yield in literature.
Killol S. Chokshi*, Divyesh B. Ladola, Aditya J. Purohit, Jaimin S. Suthar, Pratha K. Patel, Anupsinh J. Solanki and Rajiv Kukkar
Indukaka Ipcowala College of Pharmacy, New V.V. Nagar, Gujarat, India
13 June, 2012
21 August, 2012
26 September, 2012
01 October, 2012