FOSTERED ANTIARTHRITIC UPSHOT OF MORINGA OLEIFERA LAM. STEM BARK EXTRACT IN DIVERSELY INDUCED ARTHRITIS IN WISTAR RATS WITH PLAUSIBLE MECHANISMAbstract
The present research exertion was undertaken to evaluate the antiarthritic effect of methanolic extract of Moringa oleifera Lam stem bark. The extract was subjected to preliminary phytochemical investigation and antiarthritic activity was evaluated with turpentine oil, formaldehyde and CFA induced arthritis. Other parameter like body weight and hematological estimation were carried out.The result indicated that the methanolic extract of Moringa oleifera has excellent antiarthritic activity against turpentine oil, formaldehyde and CFA induced arthritis. The all groups of animals showed increase in the body weight except arthritis control and hematological perturbations indued by CFA were maintained. The complete result indicated that Moringa oleifera methanolic extract possesses a potent protective effect against turpentine oil, formaldehyde and CFA induced arthritis. The consequences of the present investigation proved well thatMoringa oleifera methanolic extract is effective in the treatment of rheumatoid arthritis and that it support the common belief prevailing in traditional medicine world wide.
Vikas Kumar*, Amita Verma , Danish Ahmed, Nikhil Kumar Sachan , Firoz Anwar and Mohd. Mujeeb*
Department of Phytochemisty & Pharmacognosy, Faculty of Pharmacy, Jamia Hamdard , New Delhi- 110 062, India
14 March, 2013
10 July, 2013
29 September, 2013
01 October, 2013