FREE RADICAL SCAVANGING ACTIVITY OF RASASINDURA (RED SULPHIDE OF MERCURY)Abstract
The main aim of the study was to scientifically validate the free radical scavenging activity of classically prepared Rasasindura (Red sulphide of mercury). With this intention Rasasindura (Red sulphide of mercury) was subjected to the screening of free radical scavenging activity in rat’s liver homogenate with four parameters like lipid peroxidation (LPO), super oxide dismutase (SOD), catalase (CAT) and reduced glutathiosone (GSH). In lipid peroxidation assay maximum decrease in concentration of MDA was seen in 1% of Rasasindura suspension in 1st, 2nd and 4th day of study. There was no significant difference when control and test sample compared with standard drug, this shows that the action of standard and test samples were same in concentration of SOD and GSH. 1% and 5% of Rasasindura has shown significant decomposition of H2O2 in 4th and 2nd day respectively when compared to standard group. There was no significant difference when control and test compared with standard drug. This shows that the action of standard and test drugs were same in decrease of elevated GSH level with all the concentrations.
V. B. Kupati * and P. G. Jadar
Department of Rasashastra and Bhaishajyakalpana, KAHER’S Shri B. M. Kankanawadi Ayurveda Mahavidyalaya, A Constituent Unit of KLE Academy of Higher Education and Research, Belgavi, Karnataka, India.
28 November, 2017
18 June, 2018
29 June, 2018
01 August, 2018