FREE RADICAL SCAVENGING AND ANTIBACTERIAL EVALUATION OF PTEROCARPUS SANTALINUS LEAF IN-VITRO STUDYAbstract
The present study was designed to investigate the antibacterial activity and free radical scavenging potential of methanloic extract of Pterocarpus santalinus (PSMExt). Significant MIC was observed against Bacillus subtilis (0.312 mg/ml). Free radical scavenging potential of PSMExt was evaluated by using total antioxidant activity (thiocyanate method), diphenyl-picryl-hydrazyl (DPPH) assay and nitric oxide (NO) assay. Results of the present study disclosed that PSMExt showed remarkable and concentration dependent free radical scavenging activity. Phytochemical analysis showed the presence of flavonoids, terpenoids and steroids. The present work indicated that the methanolic extract of Pterocarpus santalinus was capable of scavenging the free radicals and inhibited the tested bacteria, suggested the potential antibacterial and antioxidant effect.
Jenive Stella , P. Krishnamoorthy*, A. Jamal Mohamed , M. Anand
Asst. Prof., Department of Zoology, Rajah Serfoji Government College, Thanjavur, India
27 January, 2011
06 March, 2011
06 April, 2011
01 May, 2011