FUSED HETEROCYCLES AS A POTENT BIOLOGICAL AGENTS; RECENT ADVANCEMENTAbstract
Recently the synthesis of fused heterocyclic compounds seeks great attention of researches in the field of medicinal chemistry. Majority of the drug compounds contains heterocyclic ring in their structures and these heterocyclic skeleton contributes significantly in the biological profile of drug. The heterocyclic compound play significant role in synthetic chemistry and many heterocyclic derivatives have been successfully synthesized as potent drug molecule. Many researchers have focused on the synthesis of fused heterocyclic compounds considering the beneficial property of fused derivatives and some of the fused heterocyclic compounds were found to possess potent biological action such as; antibacterial, antiallergic, anti-inflammatory, antitumor and antiparkinsonism etc. The basis of synthesizing fused heterocyclic derivatives resides in the fact that combination of two molecules or incorporation of new molecule in previously bio-active compound may potentiate action of each other synergistically, sometimes fusion leads formation of derivatives with newer biological profile other than the combining structure. This review article covers the most active heterocyclic compounds which possess considerable biological activities
Upendra Bhadoriya* and Dinesh Kumar Jain
College of Pharmacy, IPS Academy, Rajendra Nagar, A. B. road, Indore (M.P.), India.
26 May, 2015
21 March, 2016
03 April, 2016
01 May 2016